Organic Chemistry and Genetics Problems

1. Write the structural formula for each of the following:
a) thymine
b) guanine
c) the nucleoside formed from the combination of guanine and 2-deoxy-D-ribose (referred to as 2'-deoxyguanosine)

2. Write an equation for the complete hydrolysis of 2'-deoxythymidine-5'-monophosphate (dTMP) to its component parts.

3. The base pairing between G-C bases is stronger than that between A-T bases. Why is that?

4. A segment of DNA contains the following base sequence: 5' T-C-G-T-A-C-C 3'
Draw the sequence of the complimentary segment and label its 3' and 5' ends.

5. For the DNA segment in problem 4, write the mRNA complement and label its 3' and 5' ends.

6. Name two biologically important nucleotides and describe their biological functions.

7. Describe the role of mRNA in protein synthesis.