Naproxen belongs to a class of pahrmaceuticals, the (S)-(+)-enantiomer is the desired pharmacological activity while the (R)-(-) -enantiomer is potentially a liver toxin. Due to this, commercial Naproxen is sold as the S-(+)-enantimoer with high levels of optical purity.
Calculate the observed rotation (a) for naproxen from the following information:
%S= 95% (a) literature= +66.0
Concentration = 35g/78mL path length=2dm