Look at the gene sequence below and try to answer the following questions based on your knowledge of amino acids: Which of these mutations do you think will not cause any consequences? Which are more drastic? Look at the amino acid sequences and use your knowledge of charges and structure to help you answer this question.

Original Sequence 

(note that spacing and color is to aid in identifying codons and mutations, respectively)

AUG AAC CAG GGG UGG UGU CGA CCA AUA GUG CCC UCU UUU UAC GGU UAC UUG CCG CGG UAG

Mutations

1

AUG AAC CAG GGG UGG UGU CGA CCA AUA GUG CCC ACU UUU UAC GGU UAC UUG CCG CGG UAG

2

AUG AAC CAG GGG UGG GUG UCG ACC AAU AGU GCC CUC UUU UUA CGG UUA CUU GCC GCG GUA G

3

AUG AAC CAG GGG UGG UGU CGA CCA AUA GUG CCC UCU UUU UAG GGU UAC UUG CCG CGG UAG

4

AUG AAC CAG GGG UGG UGU AGA CCA AUA GUG CCC UCU UUU UAC GGU UAC UUG CCG CGG UAG

5

AUG AAC CAG GGG UGA UGU CGA CCA AUA GUG CCC UCU UUU UAC GGU UAC UUG CCG CGG UAG