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Explain where in the citric acid cycle a hypothetical defect of the enzyme citrate synthase could occur that could decrease the overall ATP production.

If this enzyme is defective, what happens to the levels of the enzymes products.

How does this impact the cycle as a whole? Can the cycle continues or does it stops?

What happens to NADH and FADH2 production?

What happen to the electron transport chain and ATP production?

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