Look up the structure of ibuprofen. Design a synthesis of ibuprofen based on commercially available starting materials. 3.) One of the side effects of taking non-steroidal anti-inflammatories like aspirin and ibuprofen is a degradation of the integrity of the stomach lining. This is because the cyclooxygenase-1 (COX-1) enzyme responsible for part of the signaling cascade that leads to replenishment of the stomach lining is inhibited by these drugs. How does it differ from the COX-2 enzyme responsible for inflammation?