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Stabilization of DNA strand by histones
The typical length of a DNA strand is 3.4cm. In order to fit into a cell, the DNA strand is supercoiled around proteins called histones. Histones are a family of five proteins thet are rich in the amino acids and lysine. How do histones stabilize the DNA strand? (look at the backbone of the DNA strand at the molecular level.)

Does a mutation causing a substitution of one base pair in a strand of DNA necessarily result in a new amino acid in the protein coded for that gene? Explain.

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