problem 1) Classify Anticonvulsants with exs. Describe mechanism of action and SAof any three classes.

problem 2) describe the pharmacological actions, chemistry, SAR and metabolism of acetyl choline.

problem 3) Outline the synthesis of the following:

i) Phenyl butazone

ii) Amantadine

iii) Nifedipine

iv) Clonidine

v) Methadone

vi) Phenytoin.

problem 4) prepare brief notes on:

i) General anaesthetics

ii) Concept of prodrug

iii) MAO inhibitors

iv) Receptor site theories

problem 5) Classify antihypertensive agents giving suitable exs. Add a note on ACE inhibitors as antihypertensive agent.

problem 6) What are CNS stimulants ? Classify them. describe the chemistry, SAR, MOA of each class in brief with suitable exs.

problem 7) Define the term ‘Hormones’. describe the chemistry and biological actions of adrenocorticoids.

problem 8) prepare short notes on:

i) Tricyclic antidepressants

ii) Analeptics

iii) Cardiac glycosides

iv) Parkinsonism