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Consider the malate dehydrogenase reaction from the citric acid cycle. Given the following concentrations, calculate the free energy change for this reaction at 37.0 °C (310 K). ?G°' for the reaction is 29.7 kJ/mol. Assume that the reaction occurs at pH 7.

[malate] = 1.31 mM
[oxaloacetate] = 0.160 mM
[NAD ] = 460 mM
[NADH] = 180 mM

?G=?

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