+1-415-315-9853

info@mywordsolution.com

 Algebra Math Calculus Physics Chemistry Biology Earth Science Physiology History Humanities English Sociology Nursing Science

Pharmacodynamics is the word employed to describe the effect that a drug has on the body. It finds out whether the drug is going to be efficient in the treatment of disease with minimum side-effects. The initial step leading to a drug response is binding of a drug to its receptor. This drug receptor interaction is followed by the sequence of intracellular events which outcomes in the response of the cell to drug.

Pharmacokinetics is the word employed to describe the effect the body, its organs and tissues has on the action of a drug once it is administered. It is not usual for the similar amount of drug to be finally available at its site of action. As soon as the drug enters the body, the body will act on the drug to modify its concentration and in most of the cases its chemical structure. In order to be able to use drugs wisely and at proper doses we require understanding the pharmacokinetics of the drug. To exert an effect on the body, a drug should reach its target tissue in a proper form, and in adequate concentration, to initiate a particular therapeutic effect. Once the pharmacokinetics of a drug is known it is then possible to find out:

• The doses (or concentrations) to be given to the patient.
• The most efficient route of administration.
• How often the dose has to be given in order to get maximum therapeutic advantage for the patient.

The exclusive characteristics of each patient can affect both the pharmacokinetics and pharmacodynamics processes comprised in the drug action. They can as well find out the patient’s response. Sources of individual variation comprise:

• Interactions between the drugs if the patient is getting more than one drug at similar time.
• Physiological variables like age, sex and weight.
• Patho-physiological variables related to the disease (especially reduced function of kidney and liver, which are the main organs of drug elimination).
• Genetic variables that can modify the metabolism of drugs and predispose the patient to exclusive side-effects which can’t be predicted.

Whenever we consider all of the possible uncontrolled variables related with the treatment of an individual patient – like the patient’s disease and the multiple pharmacological effects of most of the drugs – it is simple to believe that any attempt at rational drug therapy is not possible. To the inexperienced and untrained student initial encounters with the drug treatment might appear as the best guess on the part of clinical team backed up by years of clinical experience of what drugs have worked in the past on patients with an alike illness. Luckily, this is not true. Of all branches of practical medicine it is perhaps the therapeutic feature of patient care with drugs which is most amenable to objective research. For illustration we can:

• Intervene the patient’s disease with a drug.
• Objectively measure the response to drug.

Use the data obtained from one group of patients to build up and inform good practice for the use of the drug in other patients.

Whenever we administer a medicine to a patient the active drug itself is only one variable in the complex pattern of events which will determine how that individual patient responds. This is important, therefore, that we spend time considering all of the factors that might happen to our therapeutic objective among the writing of the prescription and the patient’s final response to the drug.

By using the above information and also information from your own sources, describe the difference between the Pharmacodynamics and Pharmacokinetics in detail.

• Category:- Biology
• Reference No.:- M99547

Have any Question?

## Related Questions in Biology

### Transgenic organismsthe development of transgenic organisms

Transgenic Organisms The development of transgenic organisms is an established technique in many laboratories. A transgenic organism is an organism that includes DNA from another organism in the cells of its body. This D ...

### Cell cycle checkpoints are an important feature of a

Cell cycle checkpoints are an important feature of a dividing cell to reduce errors that can occur in various stages of the cell cycle. Loss of Rb, an important part of the G1-S transition checkpoint, can result in uncon ...

### In anotherchapter you will learn of evidence that primates

In anotherchapter, you will learn of evidence that primates, especially fossil species in the Hominin group that apparently led to our currentHomo sapiens sapiensspecies identity. Many of the fossils of pre-human species ...

### 1 what are some methods doctors have used to try and

1. What are some methods doctors have used to try and control acupuncture? What factors have helped or hindered them in this attempt? Your response should be at least 75 words in length. 2. Describe the difference that e ...

### Select one of the topics research the topic thoroughly and

Select One of the Topics, Research the Topic Thoroughly and Write a Concise Research Paper Companion Animal Medicine Most of the concepts that apply to humans also apply to our companion animal friends, an important thin ...

### The ability of a person to roll their tongue is controlled

The ability of a person to roll their tongue is controlled by a single gene with two alleles. About 65% of people have the dominant allele, and can therefore roll their tongue. Stephanie cannot roll her tongue. Without y ...

### Digestion is an important process in the human bodya

Digestion is an important process in the human body. a) Identify and describe the digestive processes. b) Consider the mouth, stomach, small intestines and large intestines - identify the digestive enzymes that are prese ...

### Describe two relic structures in mans anatomy that reflect

Describe two relic structures in man's anatomy that reflect our common evolution history with animals.

### A multicellular lifeform has a weird type of cell in its

A multicellular lifeform has a weird type of cell in its body. This cell has a high density of peroxisomes. What is the most reasonable function of this cell? Functions for redox reactions Functions for digestion Functio ...

### What is the basic building block of a sanitary landfill how

What is the basic building block of a sanitary landfill? How is it constructed? Make a sketch to illustrate your answer. What kind of equipment or machinery is used to construct and operate a landfill?

• 13,132 Experts

## Looking for Assignment Help?

Start excelling in your Courses, Get help with Assignment

Write us your full requirement for evaluation and you will receive response within 20 minutes turnaround time.

### WalMart Identification of theory and critical discussion

Drawing on the prescribed text and/or relevant academic literature, produce a paper which discusses the nature of group

### Section onea in an atwood machine suppose two objects of

SECTION ONE (a) In an Atwood Machine, suppose two objects of unequal mass are hung vertically over a frictionless

### Part 1you work in hr for a company that operates a factory

Part 1: You work in HR for a company that operates a factory manufacturing fiberglass. There are several hundred empl

### Details on advanced accounting paperthis paper is intended

DETAILS ON ADVANCED ACCOUNTING PAPER This paper is intended for students to apply the theoretical knowledge around ac

### Create a provider database and related reports and queries

Create a provider database and related reports and queries to capture contact information for potential PC component pro