Ask Question, Ask an Expert

+1-415-315-9853

info@mywordsolution.com

Ask Biology Expert

Pharmacodynamics is the word employed to describe the effect that a drug has on the body. It finds out whether the drug is going to be efficient in the treatment of disease with minimum side-effects. The initial step leading to a drug response is binding of a drug to its receptor. This drug receptor interaction is followed by the sequence of intracellular events which outcomes in the response of the cell to drug.

Pharmacokinetics is the word employed to describe the effect the body, its organs and tissues has on the action of a drug once it is administered. It is not usual for the similar amount of drug to be finally available at its site of action. As soon as the drug enters the body, the body will act on the drug to modify its concentration and in most of the cases its chemical structure. In order to be able to use drugs wisely and at proper doses we require understanding the pharmacokinetics of the drug. To exert an effect on the body, a drug should reach its target tissue in a proper form, and in adequate concentration, to initiate a particular therapeutic effect. Once the pharmacokinetics of a drug is known it is then possible to find out:

  • The doses (or concentrations) to be given to the patient.
  • The most efficient route of administration.
  • How often the dose has to be given in order to get maximum therapeutic advantage for the patient.

The exclusive characteristics of each patient can affect both the pharmacokinetics and pharmacodynamics processes comprised in the drug action. They can as well find out the patient’s response. Sources of individual variation comprise:

  • Interactions between the drugs if the patient is getting more than one drug at similar time.
  • Physiological variables like age, sex and weight.
  • Patho-physiological variables related to the disease (especially reduced function of kidney and liver, which are the main organs of drug elimination).
  • Genetic variables that can modify the metabolism of drugs and predispose the patient to exclusive side-effects which can’t be predicted.

Whenever we consider all of the possible uncontrolled variables related with the treatment of an individual patient – like the patient’s disease and the multiple pharmacological effects of most of the drugs – it is simple to believe that any attempt at rational drug therapy is not possible. To the inexperienced and untrained student initial encounters with the drug treatment might appear as the best guess on the part of clinical team backed up by years of clinical experience of what drugs have worked in the past on patients with an alike illness. Luckily, this is not true. Of all branches of practical medicine it is perhaps the therapeutic feature of patient care with drugs which is most amenable to objective research. For illustration we can:

  • Intervene the patient’s disease with a drug.
  • Objectively measure the response to drug.

Use the data obtained from one group of patients to build up and inform good practice for the use of the drug in other patients.

Whenever we administer a medicine to a patient the active drug itself is only one variable in the complex pattern of events which will determine how that individual patient responds. This is important, therefore, that we spend time considering all of the factors that might happen to our therapeutic objective among the writing of the prescription and the patient’s final response to the drug.

By using the above information and also information from your own sources, describe the difference between the Pharmacodynamics and Pharmacokinetics in detail.

Biology, Academics

  • Category:- Biology
  • Reference No.:- M99547

Have any Question? 


Related Questions in Biology

How to apply kantian and utilitarian theories to the

How to apply Kantian and Utilitarian theories to the situation that existed at Memorial Medical Center in the days immediately after Hurricane Katrina, was Dr. Anna Pou's treatment of the LifeCare patients on the seventh ...

In preparation for this assignment please visit each of the

In preparation for this Assignment, please visit each of the following websites to learn about how HIV wreaks havoc on the human immune system. Aids.gov. Overview of HIV Treatments. Retrieved fromhttps://aids.gov/hiv-aid ...

How does complementary base pairing facilitate dna

How does complementary base pairing facilitate DNA replication and the processes of transcription and translation? Identify the base pairs in each process.

Weve all had experiences where we have been frustrated by a

We've all had experiences where we have been frustrated by a decision that our supervisor made. You have probably blamed this decision on your boss being "closed-minded," "stubborn," or "pigheaded." But after reading the ...

Arrange the gram staining steps in their correct order only

Arrange the gram staining steps in their correct order (only write the correct alphabetical order. Write the answer as the correct order of letters. a. Saffranine b. Air dry c. Heat fix d. Crystal violet e. Decolorize f. ...

What are the transcription factors important for muscle

What are the transcription factors important for muscle development? i.e. There are different steps to get a muscle fiber, what are the transcription factors that are important for these steps?

1 what are the benefits of sequencing the genome of an

1) What are the benefits of sequencing the genome of an organism? Explain by giving 3 examplesfor the applications of genomic information. 2) Why do not modern apes become human today? World limit is between 250-400

Jerry coyne proposes a question at what point are the

Jerry Coyne proposes a question. At what point are the differences between populations large enough to make us call them different species? please answer question and defend answer.

Trace the path of a sperm out of the male body and the path

Trace the path of a sperm out of the male body and the path of a sperm into the female body to an oocyte.

The primary goal of the reproductive system is the

The primary goal of the reproductive system is the production of a new human being. Let's consider each step of that process, beginning with the formation of gametes (sperm and eggs) and ending with birth. Can someone st ...

  • 4,153,160 Questions Asked
  • 13,132 Experts
  • 2,558,936 Questions Answered

Ask Experts for help!!

Looking for Assignment Help?

Start excelling in your Courses, Get help with Assignment

Write us your full requirement for evaluation and you will receive response within 20 minutes turnaround time.

Ask Now Help with Problems, Get a Best Answer

Section onea in an atwood machine suppose two objects of

SECTION ONE (a) In an Atwood Machine, suppose two objects of unequal mass are hung vertically over a frictionless

Part 1you work in hr for a company that operates a factory

Part 1: You work in HR for a company that operates a factory manufacturing fiberglass. There are several hundred empl

Details on advanced accounting paperthis paper is intended

DETAILS ON ADVANCED ACCOUNTING PAPER This paper is intended for students to apply the theoretical knowledge around ac

Create a provider database and related reports and queries

Create a provider database and related reports and queries to capture contact information for potential PC component pro

Describe what you learned about the impact of economic

Describe what you learned about the impact of economic, social, and demographic trends affecting the US labor environmen