AIDS drugs such as Indavir and Amprenavir act by 1. inhibiting an enzyme that catalyzes the cleavage of a peptide bond between the gag and pol fragments in the gag-pol protein.2 2.catalyzing the cleavage of a peptide bond between the gag and pol fragments of the gag-pol protein. 3. promoting the destruction of HIV protease. 4. inhibiting an enzyme that catalyzes the cleavage of the peptide bond to the terminal amino acid in the gag-pol protein. 5. binding to the gag-pol protein thus protecting the peptide bond between the gag and pol fragments.