1. The main trial is conducted and involves a total of 200 patients. Patients are enrolled and randomized to receive either the experimental medication or the placebo. The data shown below are data collected at the end of the study after 6 weeks on the assigned treatment.
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Experimental (n=100)
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Placebo (n=100)
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Mean (Std Dev) Systolic Blood Pressure
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120.2 (15.4)
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131.4 (18.9)
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% Hypertensive
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14%
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22%
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% With Side Effects
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6%
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8%
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- Generate a 95% confidence interval for the difference in mean systolic blood pressures between groups.
- Generate a 95% confidence interval for the difference in proportions of patients with hypertension between groups.
- Generate a point estimate for the relative risk of side effects in patients assigned to the experimental group as compared to placebo. Generate a 95% confidence interval for the relative risk.