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1. Describe the transmission of pertussis (whooping cough) in the context of the Agent-Host-Environment triangle.

2. Describe he golbal epidemiology of pertussis, and identify the most important changes in disease burden observed in the past 2-3 decades in developed countries/regions.

3. Provide an ecidence-based explanation for the observed patterns of pertussis decribed above (you can choose one country/ region as an examle to illustrate), and propose potential interventions to control the disease in response to the chnages in disease pattern.

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