The disease Cholera multiplies intestinally producing a cholera toxin protein. This cholera toxin protein enters cells lining the intestine and modifies subunits of a certain G protein which prevents it from hydrolyzing its bound GTP. This results in excessive outflowing of Cl- and H2O into the gut, followed by dehydration and diarrhea.

Without describing specific intracellular signaling molecules, what effect does cholera toxin have on a signaling pathway?