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You just received funding from the EPA to conduct a study to see if there is a link between air pollution and lung disease. How would you design a study that is not weakened by the ecologic fallacy? (Include the following considerations: definition and measurement of the exposure and the outcome, unit of analysis, and sample selection). The target population are children in the West-Los Angeles and Midwest-Detroit regions of the United States. Guidence and references to this question is greatly needed and welcomed.

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