When a transgene is used in mice to knock out a specific, Ask an Expert

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When a transgene is used in mice to knock out a specific function, two problems that might occur are the unintended introduction of multiple copies, or abnormal gene expression. In this case, abnormal gene expression is related to which of the following mechanisms?

A) Position effect. B) Homologous recombination. C) Vector insufficiency. D) Mitotic recombination. E) Unequal crossing over. please explain!

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