(Answered) What are the psychological effects of substance abuse on

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What are the psychological effects of substance abuse on the Addict and Co-Addict? Please explain even if just one or two statement. I've listed depression, paranoia, need to get their next fix and anxiety for the addict. And enabling, controlling, trying to fix or save and feeling of guilt. But someone is asking to explain the process that occurs to creates the psychological problems?

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