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problem 1) What are clinical trials ? describe different phases of clinical trials.

problem 2) describe dosage form. Describe in detail classification of dosage form. Add a note on sustained release and targeted drug delivery system.

problem 3) Attempt the following:

a) describe pharmaceutics and describe its scope.

b) What is first pass effect?

c) Add a note on drug efficiency and dose response concept.

d) Mention applications of radiopharmaceuticals.

e) Give the importance of GMP.

f) Describe principle of Unani and Siddha system of medicine.

g) describe antioxidants used in formulation.

problem 4) prepare brief notes:

a) Packaging of tablet

b) Concept of preformulation

c) Bio-availability and bio-equivalence

d) Development of profession of pharmacy

e) Routes of administration

problem 5) What are aromatic waters? Describe the methods of preparation and preservation of aromatic waters.

problem 6) describe the principle, construction, working, advantages and applications of plate and frame filter press.

problem 7) Answer the following problems

a) Describe why preservatives are not required in simple syrup I.P.

b) Discuss formulation of linctuses.

c) describe factors affecting size reduction.

d) prepare a detail note on propeller mixer.

e) describe the importance of filter aids.

f) Describe different methods of granulation.

g) prepare a note on tooth powder.

problem 8) Answer the following problems:

a) describe the process of size gradation and size distribution.

b) describe construction, working and application of Ball mill.

c) Discuss formulation and manufacturing process involved in liquid oral preparation.

d) prepare note on:

i) Rotary filter

ii) Planetary mixer.

e) Discuss methods used for improvement of solubility.

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