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The following are true for chemical disposition: 

a. highly-charged chemicals do not cross biological membranes 
b. chemical absorption is more rapid by inhalation than by oral route 
c. most lipid soluble chemicals are absorbed via passive diffusion 
d. the vinegar:water partition coefficient is a measure of the hydrophobicity of a compound 
e. all other things equal, a long carbon chain compound has a higher partition coefficient that a shorter carbon chain compound.

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