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The diagnoses of depression has been made for a 57 year of age white male with symptoms of insomnia, anxiety, hoplessness, suicidal ideation and anhedonia for the last 4 weeks. His medical history indicates a myocardial infarcation )"heart attack") 2 yesrs ago and he now takes nitroglycerin (Nitrostat) prn for angina and chest pain and warfarin (Coumadin) for inhibition of platelet aggregation. He has been diagnosed with Hepatitis C. What is your opinion for the safest antidepressant for this patient's treatment?

1) Doxepin (Sinequan)
2) Trazodone (Desyrel)
3) Fluoxetine (Prozac)
4) Nefazodone (Serzone)
5) Citalopram (Celexa)

What is the rationale for your answer?

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