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Question 1 - Which class of anti AIDS drugs is used to prevent the virus from integrating into the host genome so that it can live indefinitely in a dormant state inside the host? (More than 1 options can be correct)

Nucleoside reverse transcriptase inhibitor

Non-nucleoside reverse transcriptase inhibitor

Protease inhibitor

Integrase inhibitor

Fusion inhibitor

CCR5 inhibitor

Question 2 - Which class of drug interferes with the maturation of the virus by preventing a long nonfunctional polypeptide from being cut into three separate functional proteins? (More than 1 options can be correct)

Nucleoside reverse transcriptase inhibitor

Non-nucleoside reverse transcriptase inhibitor

Protease inhibitor

Integrase inhibitor

Fusion inhibitor

CCR5 inhibitor

Question 3 - What is the major limitation in the use of Nucleoside Reverse Transcriptase Inhibitors (NRTIs) for AIDS treatment?

Question 4 - What is the approximate annual cost of triple combination therapy for HIV infection

$2,000

$5,000

$15,000

$25,000

Question 5 - Read the article in the Module 8 Learning Materials entitled New hope for babies with HIV:

Article - Rare case of 9-year-old in HIV remission for years -- without drugs By Meera Senthilingam, CNN

Discuss the the study. Answer the following questions in your discussion:

1. Describe the study and the results.

2. Give your personal opinion about this strategy for short-term treatment.

3. Do you think this might be a promising treatment for babies in third world countries, since lifelong treatment with triple combination therapies can be too expensive?

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