Question: Consider the following case study:

Patient AO has a history of obesity and has recently gained 9 pounds. The patient has been diagnosed with hypertension and hyperlipidemia. Drugs currently prescribed include the following:

• Atenolol 12.5 mg daily

• Doxazosin 8 mg daily

• Hydralazine 10 mg qid

• Sertraline 25 mg daily

• Simvastatin 80 mg daily

To prepare:

• Review this week's media presentation on hypertension and hyperlipidemia, as well as Chapters 19 and 20 of the Arcangelo and Peterson text.

• Select one one the following factors: genetics, gender, ethnicity, age, or behavior factors.

• Reflect on how the factor you selected might influence the patient's pharmacokinetic and pharmacodynamic processes.

• Consider how changes in the pharmacokinetic and pharmacodynamic processes might impact the patient's recommended drug therapy.

• Think about how you might improve the patient's drug therapy plan based on the pharmacokinetic and pharmacodynamic changes. Reflect on whether you would modify the current drug treatment or provide an alternative treatment option for the patient.

With these thoughts in mind:

Post an explanation of how the factor you selected might influence the pharmacokinetic and pharmacodynamic processes in the patient from the case study. Then, describe how changes in the processes might impact the patient's recommended drug therapy. Finally, explain how you might improve the patient's drug therapy plan.

- This work should have Introduction and conclusion

- This work should have at 3 to 5current references (Year 2012 and up)

- Use at least 2 references from class Learning Resources

The following Resources are not acceptable:

1. Wikipedia

2. Cdc.gov- nonhealthcare professionals section

3. Webmd.com

4. Mayoclinic.com