Question 1. The major impact of the physiological changes that occur with aging is:
Reduced physiological reserve
Reduced homeostatic mechanisms
Impaired immunological response
All of the above

Question 2. Men have faster and more efficient biotransformation of drugs and this is thought to be due to:
Less obesity rates than women
Prostate enlargement
Testosterone
Less estrogen than women

Question 3. The cytochrome p system involves enzymes that are generally:
Inhibited by drugs
Induced by drugs
Inhibited or induced by drugs
Associated with decreased liver perfusion

Question 4. Functional abilities are best assessed by:
Self-report of function
Observed assessment of function
A comprehensive head-to-toe examination
Family report of function

Question 5. Iron Deficiency Anemia (IDA) is classified as a microcytic, hypochromic anemia. This classification refers to which of the following laboratory data?
Hemoglobin and Hematocrit
Mean Corpuscular Volume (MCV) and Mean Corpuscular Hemoglobin (MCH)
Serum ferritin and serum iron
Total iron binding capacity and transferrin saturation

Question 6. When interpreting laboratory data, you would expect to see the following in a patient with Anemia of Chronic Disease (ACD):
Hemoglobin <12 g/dl, MCV decreased, MCH decreased
Hemoglobin >12 g/dl, MCV increased, MCH increased
Hemoglobin <12 g/dl, MCV normal, MCH normal
Hemoglobin >12 g/dl, MCV decreased, MCH increased

Question 7. The pathophysiological hallmark of ACD is:
Depleted iron stores
Impaired ability to use iron stores
Chronic unable bleeding
Reduced intestinal absorption of iron

Question 8. The main focus of treatment of patients with ACD is:
Replenishing iron stores
Providing for adequate nutrition high in iron
Management of the underlying disorder
Administration of monthly vitamin B12 injections

Question 9. In addition to the complete blood count (CBC) with differential, which of the following laboratory tests is considered to be most useful in diagnosing ACD and IDA?
Serum iron
Total iron binding capacity
Transferrin saturation
Serum ferritin

Question 10. Symptoms in the initial human immunodeficiency virus (HIV) infection include all of the following except:
Sore throat
Fever
Weight loss
Headache

Question 11. Essential parts of a health history include all of the following except:
Chief complaint
History of the present illness
Current vital signs
All of the above are essential history components

Question 12.Which of the following clinical reasoning tools is defined as evidence-based resource based on mathematical modeling to express the likelihood of a condition in select situations, settings, and/or patients?
Clinical practice guideline
Clinical decision rule
Clinical algorithm
Clinical recommendation

Question 13. The first step in the genomic assessment of a patient is obtaining information regarding:
Family history
Environmental exposures
Lifestyle and behaviors
Current medications

Question 14.In autosomal recessive (AR) disorders, individuals need:
Only one mutated gene on the sex chromosomes to acquire the disease
Only one mutated gene to acquire the disease
Two mutated genes to acquire the disease
Two mutated genes to become carriers

Question 15. In AR disorders, carriers have:
Two mutated genes; two from one parent that cause disease
A mutation on a sex chromosome that causes a disease
A single gene mutation that causes the disease
One copy of a gene mutation but not the disease

Question 16. A woman with an X-linked dominant disorder will:
Not be affected by the disorder herself
Transmit the disorder to 50% of her offspring (male or female)
Not transmit the disorder to her daughters
Transmit the disorder to only her daughters

Question 17. According to the Genetic Information Nondiscrimination Act (GINA):
Nurse Practitioners (NPs) should keep all genetic information of patients confidential
NPs must obtain informed consent prior to genetic testing of all patients
Employers cannot inquire about an employee's genetic information
All of the above

Question 18. Which of the following would be considered a "red flag" that requires more investigation in a patient assessment?
Colon cancer in family member at age 70
Breast cancer in family member at age 75
Myocardial infarction in family member at age 35
All of the above

Question 19. Your 2-year-old patient shows facial features, such as epicanthal folds, up-slanted palpebral fissures, single transverse palmar crease, and a low nasal bridge. These are referred to as:
Variable expressivity related to inherited disease
Dysmorphic features related to genetic disease
De novo mutations of genetic disease
Different penetrant signs of genetic disease

Question 20.In order to provide a comprehensive genetic history of a patient, the NP should:
Ask patients to complete a family history worksheet
Seek out pathology reports related to the patient's disorder
Interview family members regarding genetic disorders
All of the above