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People with co-occurring physical and mental conditions represent a significant portion of the U.S. population.

According to The Synthesis Project: New Insights From Research Results, physical disorders may lead to mental disorders, and physical conditions may place a person at risk for certain mental disorders.

Mental and physical disorders may share common risk factors.

With this information in mind, explain the following statement: "The pathways causing comorbidity is complex and bidirectional."

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