In the paper on mature bdnf vs probdnf in synapse, Ask an Expert

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In the paper on mature BDNF vs proBDNF in synapse competition by Je et al., PNAS, 109:15924-9. The authors suggest that mature BDNF promotes synapse stabilization.

1) Suggest one general mechanism to explain how BDNF might stabilize a synapse. In your explanation, state one specific hypothesis that you could experimentally test.

2) Describe one experiment to test your hypothesis.

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