I was just taken off of my 2 year maintenance of Rituxan. The reason was after receiving 4 treatments I started having questionable neurological issues. Nothing major. The oncologist sent me to have a brain scan. A neurologist read it an said i had too much white matter showing up. So I went for a spinal tap to be tested for MS and the very scary brain virus PML. Both came back negative. The oncologist said no more Rituxan and i will get a repeat scan of my brain in 3 months to see if there are any changes. So my question is, has anyone ever had this issue? Does anyone know if Rituxan causes this "White Matter" ?