I used to suffer from UTIs frequently during my teens but was free of them for 4 years after the infection spread to my kidneys and I was prescribed strong antibiotics. During travels to the States, I started getting the well-known symptoms again - painful urination and burning without urinating, pressure, feeling low etc. and was prescribed Bactrim for 5 days. The symptoms started subsiding 2 days after completion of the antibiotics course. Then, 3 weeks later, right while I was recovering from a nasty stomach bug, the infection was back. After 5 days of symptoms, I went to a different doctor in the US who prescribed a 7 day course of ciprofloxacin (250mg twice daily)... the symptoms persisted. I am now back in the UK and have had symptoms for 3 weeks and am on a different course of antibiotics - nitrofurantoin for 7 days (4 x 50mg daily), going to finish tomorrow and the symptoms aren't getting better. All tests so far have shown high leukocyte count but no nitrites, I am still waiting for results from the urine culture. I am already nearing the end of my tether and don't know how to cope with the pain much longer. Does anyone know how I can help this?