ersonalized medicine involves the application of a patient's genomic information to determine whether a particular approach to treatment is likely to be effective for that patient and to implement the right preventative measures for that patient at the right time. The potential rami?cations of personalized medicine on the practice of health care are numerous, from the customization of drug treatment regimens based on a patient's individual genetic background to the modi?cation of health information systems to accommodate individualized approaches to clinical decision support.consider the ramifications for the provider of using this genetic information in the care and treatment of the patient, as well as its potential impact on the information systems that the provider uses for clinical decision support.

1. Should information systems change to integrate this knowledge into electronic prescribing? Why or why not?

2. How might supporting personalized medicine with health information system technology pose challenges for an organization's health information technology staff? For its health care providers?