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DNA sequencing and replication

What are the steps involved and the enzymes used in DNA replication?

In your opinion, can a disorder result from the malfunction of any enzyme used during DNA replication?

If yes, identify any one disorder and explain how it is caused. If no, why?

Can a disease result from a mutation in a transcription factor?

If so, provide at least one example, naming the transcription factor, the mutation, and the congenital defect that arises.

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