Detailed Guide to the Experiment: Pharmacology

Determination of the LD50 of an Insecticide in Cockroaches

The Task

This is a practical experiment being conducted by the student. We need to analyse data that has been collected and complete all sections other than 'Materials and Methods'.

In other words, the following is required:

1. Report Title
2. Introduction
3. Data Presentation
4. Results
5. Discussion

Requirements for Pharmacology 1 Practical Report Write-up

Reports are due two weeks after receiving final class data. The following is a checklist you should complete prior to submitting your report for grading. Use this checklist to determine if you fulfill the minimum assessment requirements. If your answer is ‘no' to any of the following criteria then you should address this issue before submission, or risk losing marks in the grading scheme.

1. General submission requirements
Is your report, including text, graphs, tables, figures and references, less than 7 pages?
Is your practical report stapled together and has your name and practical group on the front cover? Reports in plastic sleeves will not be accepted.
Is your report typed? Handwritten reports will not be accepted.
Have you submitted the electronic version via the Digital Dropbox by the due date?

2. Report Title
Do you have an appropriate title for your report? Your title should provide sufficient information to determine the aim of the experiment

3. Introduction
Does you introduction provide the necessary background to understand: why you are doing the experiment, and the details of the experiment?

Is your introduction integrated such that the background, aims (and any hypotheses) are not separated?

4. Materials and Methods
Have you summarised the experimental materials and methodology? You are not required to rewrite all of the methods.
Have you referred to the specific pages of the Pharmacology 1 practical manual for relevant procedures?
Have you provided details of any changes to the original experimental methodology (eg. changes in concentrations, purity of stock samples, number of doses employed)?

5. Data presentation - Figures and Tables
Does each table and figure have a title?
Does each figure have a legend to explain the data presented, including a legend to each symbol being used? You should provide enough detail to understand what information is being presented in each graph.
Do all axes have labels and units appropriate for the data being represented (eg. are you plotting log values, are the data concentration values or doses)?

Are data fitted with the correct type of line or curve (eg. log dose-probit/transformation - linear relationship, log dose-response - sigmoidal curve)?
Do the mean data have standard deviation values shown? Are the number of experiments or replicates mentioned in the legend?
Have you identified if the data represents mean class values or individual group data?
Where appropriate, are data that are significantly different from controls (ie. p ≤ 0.05) marked with a ‘*' symbol in tables and on graphs?
What statistical test was performed (where appropriate)?

6. Results
Have you provided a written description of your findings, which does not simply list the data in the figures and/or tables?
Have you reported all your findings - even the obvious ones?
If you have claimed that the data is ‘higher/greater' or ‘lower/less' than controls have you provided the appropriate p-values and number of replicates (eg. p ≤ 0.05, n = 5)
Have your referred to all the tables or figures in your report? If not either omit the table/figure or describe your findings

7. Discussion
Does your discussion commence with a summary of the major findings of your experiment(s)?
Have you explained you findings in the context of the wider scientific literature (eg. how do your findings compare with what is already known in this area)?
Have you referenced any previous findings? If your discussion has no references this often means that you are just rehashing a description of the patterns in your results and not an explanation of the mechanisms or implications of your results.
Have you provided any explanation of your findings, including any sources of error?
Have you discussed ways in which any errors could be avoided in the future or how the experiment could be improved?

8. Bibliography
Have you provided a bibliography?
Are in-text citations in the following format "... (Author et al., Year) ..."?
Are the references in the Bibliography in the Harvard referencing style?
Are the references in the Bibliography in alphabetical order?

Attachment:- Pharmacology.rar