Assessment Task

PART A:

1. Discuss THREE different factors that would have contributed to the emergence of bacterial resistance to ciprofloxacin. Support your answer with suitable examples.

Approximately 200 to 300 words

2. What measures do you think the government/regulatory agencies should take to prevent further increase in bacterial resistance to ciprofloxacin. Using suitable examples, discuss how such measures can be implemented in various countries where bacterial resistance to ciprofloxacin is high.

Approximately 200 to 300 words

3. A. Describe a method (other than the dissolution method; the one you used in week 1) which can be used to extract ciprofloxacin from 500 mg ciprofloxacin tablet.

B. Discuss two advantages and two disadvantages of the method you describe above to the method you used in week 1.
Approximately 300 to 400 words

4.

A. Briefly discuss why did you use 10% of acidic acid to dissolve a tablet containing 500 mg of ciprofloxacin.

B. Name two solvents (other than 10% acetic acid) that can be used to dissolve a tablet containing 500 mg of ciprofloxacin.

C. Would you have used another type of solvent to dissolve a tablet containing 750 mg of ciprofloxacin? Yes or no and why?
Approximately 100 to 200 words

5.

A. What was the amount of ciprofloxacin you found in a tablet that was used to prepare 50 µg/ml of ciprofloxacin.

B. Provide a brief summary of the method you used to determine the amount of ciprofloxacin present in a tablet containing 500 mg of ciprofloxacin.

Approximately 100 to 200 words