Propranolol is the beta blocker given to ease pain of patients with episodes of unstable angina. New drug for treatment of this disease is tested on 30 pairs of patients who are matched on one-to-one basis according to age, sex, and clinical condition and are assessed as to severity of their pain. Assume that in 15 pairs of patients, patient with new drug has less pain; and in l0 pairs of patients, patient with propranolol has less pain; and in 5 pairs of patients, pain is about same with two drugs.

Assume normality is not assumed. What nonparameiric test can be used to distinguish total heart weight of males with left-heart disease with that of normal males? Write and Implement test and report a p-value.