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It is significant to create the detailed plan of study early in development of an investigation. One part of plan is to assure adequacy of sample size. Consider the test of H0: p1 = p2 with level of significance (alpha) of 0.01 with a power which is equal to 0.90. We forecast that 20% of group 1 and 30% of group 2 will experience outcome. If we recruit the equal number of individuals in each of the groups, how many individuals do we need to study?

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