After the pilot study described in Problem2, the main trial is conducted and involves a total of 200 patients. Patients are enrolled and randomized to receive either the experimental medication or the placebo. The data shown in table 6-7 are data collected at the end of the study after 6 weeks on the assigned treatment. Generate a 95% confidence interval for the difference in proportions of patients with hypertension between groups.
A clinical trial is planned to compared an experimental mediciation designed to lower blood pressure to a placebo, before starting the trial, a pilot study is conducted involving 10 participants. The objective of the study is to assess how systolic blood pressure change untreated over time. Systolic blood pressure are mesaured at baseline and again 4 weeks later,
Computed 95% confidence interval for the mean difference in blood pressure over 4 weeks.
Baseline: 120 145 130 160 152 143 126 121 115 135
4 weeks: 122 142 135 158 155 140 130 120 124 130