Question: In Example, a statistically significant relationship was found between hormone therapy and invasive breast cancer. In the same study, the following observed counts were found for death from coronary heart disease (CHD). Carry out the five steps leading to a conclusion about whether there is a statistically significant relationship between hormone therapy and death from CHD.

                          Death from CHD?

                      Yes        No        Total

Hormones          33       8,473      8,506

Placebo             26       8,076      8,102

Total                59      16,549    16,608

Example: Breast Cancer Risk Stops Hormone Replacement Therapy Study On July 17, 2002, the Journal of the American Medical Association published the results of a study that affected the lives of millions of women. The study was the first large randomized experiment to test the effects of combined estrogen and progestin, the most commonly prescribed hormone replacement therapy for postmenopausal women.