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Applying the 5% level of importance was there a significant change in cholesterol level?

Four individuals with high levels of cholesterol went on a special crash diet avoiding high cholesterol foods as well as taking special supplements. Their total cholesterol levels earlier and after the diet were as follows-

participant

before

after

J.K.

287

255

L.M.M.

305

269

A.K.

243

245

R.O.S.

309

247

Using the 5% level of importance, was there a significant change in cholesterol level?
describe your answer to someone who has never taken a course in statistics.

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