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Applying the 5% level of importance was there a significant change in cholesterol level?

Four individuals with high levels of cholesterol went on a special crash diet avoiding high cholesterol foods as well as taking special supplements. Their total cholesterol levels earlier and after the diet were as follows-

participant	before	after
J.K.	287	255
L.M.M.	305	269
A.K.	243	245
R.O.S.	309	247

Using the 5% level of importance, was there a significant change in cholesterol level?
describe your answer to someone who has never taken a course in statistics.

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