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Applied Statistics Homework Project -

Download the data twoGenes.sav from the Week Four content area of brightspace. Each row represents data from a different sample of yeast RNA expression. The data represent the log2 fold-change in expression between yeast grown under warm and cold conditions. The two columns represent expression from two different genes. Remember how SPSS data organization works!

A. Explain in a couple of sentences what is meant by "log2 fold change." This will require you to look something up. Provide a reference that's not wikipedia. Tell what the units are for log2 fold change.

B. Create a table of descriptives that includes the following information: means, 99% confidence intervals for the means, standard errors for the means, and standard deviations. The table should have two columns (one for each gene).

C. Create two histograms and two q-q plots. How would you assess normality of these data?

D. Does Gene1 have negative log2 fold change in expression? Answer this question with a hypothesis test, using a significance level of α  = 0.05. Provide a p-value and explain how you obtained it. Provide an explanation of your conclusion: don't just say "yes" or "no" with a p-value.

E. Do Gene1 and Gene2 have different log2 fold changes in expression? Answer this question with a hypothesis test, using a significance level of α = 0.10. Provide a p-value and explain how you obtained it. Provide an explanation of your conclusion: don't just say "yes" or "no" with a p-value.

Again, you must submit two documents, a "write-up" file and a "raw results" file. Each question needs to be answered in a well-organized and readable manner in the write-up. The raw results file needs to show all work on all parts.

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