You make the decision to start her on celecoxib (Celebrex) 100 mg twice daily. How does celecoxib mechanistically and pharmacologically differ from naproxen and what might you do prior to starting celecoxib and why?

. I am a difficult grader, I expect "small research papers" each week.

In addition, you must post substantively and at a graduate student level to the threaded discussion questions, I grade for correct pharmacological information (included but not limited to mechanism of action, dose, drug interactions, etc.) posted in response to case study discussion prompt questions. I also specifically focus on whether or not you actually answered the prompt question When you discuss a drug, make absolutely sure you know the "nitty-gritty" details; otherwise, your grade will reflect that lack of knowledge and the evident lack of preparation: I will not give credit for "fluff" or "filler" information.

Three pages of irrelevant information will achieve a higher point deduction than 1 page of concise, pharmacologically correct information that specifically answers my questions. When asking for differential or primary diagnoses, medication choices, etc, I expect a brief rationale for each - simply providing a list will not suffice. I expect that each diagnosis, drug, or treatment you employ to be supported by evidence from the scholarly literature that is utilized by the practitioner (MD, NP, PA, etc.), NOT the general public. Do not support a decision using information from patient-geared sources (i.e. mayoclinic.org, WebMD, etc.).

This is a pharmacology course, and drugs discussed should have an inclusion/discussion of their known and/or theorized mechanism of action. We will heavily focus on mechanism in this course and how it directly relates to treatment and outcome of pathophysiological conditions.